2004 Publications

Moore RJ. Chamberlain RM. Khuri FR. Communicating suffering in primary stage head and neck cancer. European Journal of Cancer Care. 13(1):53-64, 2004
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Johnson FM, Garden A, Palmer JL, Kies M, Clayman G, Brumfield B, Khuri FR, Morrison W, Papadimitrakopoulou V, Diaz EM, Glisson BS. A phase II study of docetaxel and carboplatin as neoadjuvant therapy for nasopharyngeal carcinoma with early T status and advanced N status. Cancer . 100(5):991-8, 2004.
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Moore, RJ, Chamberlain, RM, Khuri FR. A Qualitative study of head and neck cancer. Supportive Care in Cancer . 12(5): 338-46, 2004.
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Khuri FR, Glisson BS, Kim ES, Statkevich P, Thall PF, Meyers ML, Herbst RS, Munden RF, Zaknoen S, Tendler C, Zhu Y, Bangert S, Thompson E, Lu C, Wang X-M, Shin DM, Kies MS, Papadimitrakopoulou V, Fossella FV, Kirschmeier P, Bishop WR, Hong WK. Phase I study of farnesyl transferase inhibitor (FTI) SCH66336 with paclitaxel in solid tumors. Clinical Cancer Research, 10: 2968-76, 2004.

Kim ES, Putnam JB, Komaki R, Walsh GL, Ro JY, Shin HJ, Truong M, Moon H, Swisher SG, Fossella FV, Khuri FR, Hong WK, Shin DM. Phase II study of a multidisciplinary approach with induction chemotherapy, followed by surgical resection, radiation therapy, and consolidation chemotherapy for unresectable malignant thymomas: final report. Lung Cancer, 44(3), 369-379, 2004.
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Chu RL, Post DE, Khuri FR, Van Meir EG. Use of replicating oncolytic adenoviruses in combination therapy for cancer. Clinical Cancer Research, 10: 5299-5312, 2004.
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Takada Y, Khuri F, Aggarwal BB. Protein farnesyltransferase inhibitor (SCH 66336) abolishes NF-κB activation induced by various carcinogens and inflammatory stimuli leading to suppression of NF-κB-regulated gene expression and upregulation of apoptosis. Journal of Biological Chemistry, 279(25): 26287-99, 2004.
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Liu X, Yue P, Khuri FR, Sun S-Y. p53 upregulates death receptor 4 expression through an intronic p53 binding site. Cancer Research (Advances in Brief), 64(15): 5078-83, 2004.
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Liao, J., Yang, G-Y., Park. E.S., Meng, X., Sun, Y., Jia, D., Seril, D.N., and Yang, C.S. Inhibition of lung carcinogenesis and effects on angiogenesis and apoptosis in A/J mice by oral administration of green tea. Nutr. & Cancer, 48: 44-53, 2004.
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Lambert, J.D., Hong, J., Kim, D. H., Mishin, V.M., and Yang, C.S. Piperine enhances the bioavailability of the tea polyphenol (-)-epigallocatechin-3-gallate in mice. Nutrition 134: 1948-1952, 2004.
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Vittal, R., Selvanayagam, Z.E., Sun, Y., Hong, J., Liu, F., Chin, K.V., and Yang, C.S. Gene expression changes induced by green tea polyphenol (-)-epigallocatechin-3-gallate in human bronchial epithelial 21BES cells analyzed by DNA microarray. Mol. Cancer Ther. 3: 1091-1099, 2004.
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Hou, Z., Lambert, J.D., Chin, K-V., and Yang, C.S. Effects of tea polyphenols on signal transduction pathways related to cancer chemoprevention. Mutation Res. 555: 3-19, 2004.
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Schinazi, R.F., Hurwitz, S.J., Liberman, I., Glazcova, Y, Mourier, N.S., Olson, J., & Keane, T. 2004. Disposition of 5-o-carboranyluracil a novel agent for the boron neutron capture therapy of prostate cancer. Nucleosides, Nuculeotides & Nucleic Acids 23:291–306 
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Sun S-Y, Hail N, Lotan R. Apoptosis as a novel target for cancer chemoprevention. J Natl Cancer Inst, 96:662-672, 2004.
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Liu X, Yue P, Zhou Z, Khuri FR, Sun S-Y. Death receptor regulation and celecoxib-induced apoptosis in human lung cancer cells. J Natl Cancer Inst, 96:1769-1780, 2004.
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Zou W, Liu X, Yue P, Zhou Z, Sporn SB, Lotan R, Khuri FR, Sun S-Y. c-Jun N-terminal kinase (JNK)-mediated induction of death receptor 5 contributes to induction of apoptosis by the novel synthetic triterpenoid methyl-2-cyano-3, 12-dioxooleana-1, 9-dien-28-oate (CDDO-Me) in human lung cancer cells. Cancer Res, 64:7570-7578, 2004.
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Chen AY , Whigham A. Validation of health status instruments. Otorhinolaryngology 2004;66(4):167-172.
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Bailey, R. E., Strausburg, J. B., and Nie, S. A new class of far-red and near-infrared biological labels based on alloyed semiconductor quantum dots. J Nanosci Nanotechnol, 4: 569-574, 2004.
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Liu, X., Yue, P., Khuri, F. R., and Sun, S. Y. p53 upregulates death receptor 4 expression through an intronic p53 binding site. Cancer Res, 64: 5078-5083, 2004.
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Fanucchi, M. and Khuri, F. R. Chemotherapy for recurrent or metastatic squamous cell carcinoma of the head and neck. Semin Oncol, 31: 809-815, 2004.
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Goldman, E. H., Chen, L., and Fu, H. Activation of apoptosis signal-regulating kinase 1 by reactive oxygen species through dephosphorylation at serine 967 and 14-3-3 dissociation. J Biol Chem, 279: 10442-10449, 2004.
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Fujii, K., Goldman, E. H., Park, H. R., Zhang, L., Chen, J., and Fu, H. Negative control of apoptosis signal-regulating kinase 1 through phosphorylation of Ser-1034. Oncogene, 23: 5099-5104, 2004.
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Plemper, R. K., Erlandson, K. J., Lakdawala, A. S., Sun, A., Prussia, A., Boonsombat, J., Aki-Sener, E., Yalcin, I., Yildiz, I., Temiz-Arpaci, O., Tekiner, B., Liotta, D. C., Snyder, J. P., and Compans, R. W. A target site for template-based design of measles virus entry inhibitors. Proc Natl Acad Sci U S A, 101: 5628-5633, 2004.
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Adams, B. K., Ferstl, E. M., Davis, M. C., Herold, M., Kurtkaya, S., Camalier, R. F., Hollingshead, M. G., Kaur, G., Sausville, E. A., Rickles, F. R., Snyder, J. P., Liotta, D. C., and Shoji, M. Synthesis and biological evaluation of novel curcumin analogs as anti-cancer and anti-angiogenesis agents. Bioorg Med Chem, 12: 3871-3883, 2004.
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Ganesh, T., Guza, R. C., Bane, S., Ravindra, R., Shanker, N., Lakdawala, A. S., Snyder, J. P., and Kingston, D. G. The bioactive Taxol conformation on beta-tubulin: experimental evidence from highly active constrained analogs. Proc Natl Acad Sci U S A, 101: 10006-10011, 2004.
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Nettles, J. H., Li, H., Cornett, B., Krahn, J. M., Snyder, J. P., and Downing, K. H. The binding mode of epothilone A on alpha,beta-tubulin by electron crystallography. Science, 305: 866-869, 2004.
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Khuri, F. R., Glisson, B. S., Kim, E. S., Statkevich, P., Thall, P. F., Meyers, M. L., Herbst, R. S., Munden, R. F., Tendler, C., Zhu, Y., Bangert, S., Thompson, E., Lu, C., Wang, X. M., Shin, D. M., Kies, M. S., Papadimitrakopoulou, V., Fossella, F. V., Kirschmeier, P., Bishop, W. R., and Hong, W. K. Phase I study of the farnesyltransferase inhibitor lonafarnib with paclitaxel in solid tumors. Clin Cancer Res, 10: 2968-2976, 2004.
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Khuri, F. R. and Lotan, R. Retinoids in lung cancer: friend, foe, or fellow traveler? J Clin Oncol, 22: 3435-3437, 2004.
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Cheng, J. D., Babb, J. S., Langer, C., Aamdal, S., Robert, F., Engelhardt, L. R., Fernberg, O., Schiller, J., Forsberg, G., Alpaugh, R. K., Weiner, L. M., and Rogatko, A. Individualized patient dosing in phase I clinical trials: the role of escalation with overdose control in PNU-214936. J Clin Oncol, 22: 602-609, 2004.
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Lee, M. J., Lambert, J. D., Prabhu, S., Meng, X., Lu, H., Maliakal, P., Ho, C. T., and Yang, C. S. Delivery of tea polyphenols to the oral cavity by green tea leaves and black tea extract. Cancer Epidemiol Biomarkers Prev, 13: 132-137, 2004.
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Nicolaou, K. C., Hao, J., Reddy, M. V., Rao, P. B., Rassias, G., Snyder, S. A., Huang, X., Chen, D. Y., Brenzovich, W. E., Giuseppone, N., O'Brate, A., and Giannakakou, P. Chemistry and biology of diazonamide A: second total synthesis and biological investigations. J Am Chem Soc, 126: 12897-12906, 2004.
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Rhee, J. C., Khuri, F. R., and Shin, D. M. Emerging drugs for head and neck cancer. Expert Opin Emerg Drugs, 9: 91-104, 2004.
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Chen, Z., Zhang, X., Li, M., Wang, Z., Wieand, H. S., Grandis, J. R., and Shin, D. M. Simultaneously targeting epidermal growth factor receptor tyrosine kinase and cyclooxygenase-2, an efficient approach to inhibition of squamous cell carcinoma of the head and neck. Clin Cancer Res, 10: 5930-5939, 2004.
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Zhang, X., Hunt, J. L., Landsittel, D. P., Muller, S., Adler-Storthz, K., Ferris, R. L., Shin, D. M., and Chen, Z. G. Correlation of protease-activated receptor-1 with differentiation markers in squamous cell carcinoma of the head and neck and its implication in lymph node metastasis. Clin Cancer Res, 10: 8451-8459, 2004.
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Gao, X., Cui, Y., Levenson, R. M., Chung, L. W., and Nie, S. In vivo cancer targeting and imaging with semiconductor quantum dots. Nat Biotechnol, 22: 969-976, 2004.
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Smith, A. M., Gao, X., and Nie, S. Quantum dot nanocrystals for in vivo molecular and cellular imaging. Photochem Photobiol, 80: 377-385, 2004.
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Nitin, N., Santangelo, P. J., Kim, G., Nie, S., and Bao, G. Peptide-linked molecular beacons for efficient delivery and rapid mRNA detection in living cells. Nucleic Acids Res, 32: e58, 2004.
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Gao, X. and Nie, S. Quantum dot-encoded mesoporous beads with high brightness and uniformity: rapid readout using flow cytometry. Anal Chem, 76: 2406-2410, 2004.
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Smith, A. M. and Nie, S. Chemical analysis and cellular imaging with quantum dots. Analyst, 129: 672-677, 2004.
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Liang, Z., Wu, T., Lou, H., Yu, X., Taichman, R. S., Lau, S. K., Nie, S., Umbreit, J., and Shim, H. Inhibition of breast cancer metastasis by selective synthetic polypeptide against CXCR4. Cancer Res, 64: 4302-4308, 2004.
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Del Gaudio, J. M. and Muller, S. Diagnosis and treatment of supraglottic laryngeal paraganglioma: report of a case. Head Neck, 26: 94-98, 2004.
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Rogatko, A., Babb, J. S., Wang, H., Slifker, M. J., and Hudes, G. R. Patient characteristics compete with dose as predictors of acute treatment toxicity in early phase clinical trials. Clin Cancer Res, 10: 4645-4651, 2004. 
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Last update: July 31st, 2008
by Robert Fu & Edwin Shin